5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, (5Z)- - Names and Identifiers
Name | 15-Keto Latanoprost
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Synonyms | 15-KETO LATANOPROST 15-Keto Latanoprost Latanoprost Impurity 5 9ALPHA,11ALPHA-DIHYDROXY-15-OXO-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC ACID ISOPROPYL ESTER propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]hept-5-enoate (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester [1R-[1α(Z),2β,3α,5α]]-7-[3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, (5Z)-
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CAS | 135646-98-9
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5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, (5Z)- - Physico-chemical Properties
Molecular Formula | C26H38O5
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Molar Mass | 430.58 |
Storage Condition | -20°C |
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, (5Z)- - Introduction
15-Keto Latanoprost (15-ketolatanoprost) is a synthetic compound that is one of the metabolites of latanoprost. Its chemical name is (5Z,9α,11α,13E,15R)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid. It has the following properties:
1. Appearance: 15-Keto Latanoprost is generally a white or yellowish solid.
2. Solubility: 15-Keto Latanoprost is soluble in some organic solvents, such as methanol, dimethyl sulfoxide and chloroform.
3. Stability: 15-Keto Latanoprost is relatively stable under dry and sealed conditions.
15-Keto Latanoprost is mainly used to treat eye diseases such as glaucoma and increased intraocular pressure. Its mechanism of action is to treat these diseases by increasing aqueous humor drainage and lowering intraocular pressure.
As for the preparation method, 15-Keto Latanoprost can be obtained by reacting latanoprost with an oxidizing agent under appropriate conditions. The specific preparation method requires more in-depth research and professional technical support.
Last Update:2024-04-09 22:09:11